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Six nutrients need extra attention on a vegan diet. This protocol turns 106 scientific sources into one clear plan — exact dosages, timing, and product selection.
The six nutrients
Vitamin B12
Vitamin D3
Omega-3 DHA/EPA
Iodine
Selenium
Creatine
Why these six — and no more
Inclusion criteria
- Structurally low intake in plant-based diets (not situational, not seasonal)
- Convergent evidence: ≥3 independent streams (meta-analyses, RCTs, biomarker studies, guidelines)
- Safe for long-term daily use (dosages well below upper limits)
- Simple to execute as a daily routine (no complex schedules or cycling)
What we evaluated and excluded
- Iron — deficiency is situational, not structural for all vegans; requires individual testing
- Zinc — adequate intake achievable through normal varied plant diet
- Calcium — achievable through fortified foods (plant milks, tofu)
- Vitamin K2 — insufficient evidence for universal supplementation
- Choline — insufficient evidence for universal supplementation
Full evaluation details: non-recommendations.json
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For developers & AI agents
- Discovery: /.well-known/protocol.json
- One-shot summary: /vegan-baseline/summary.json
- Full decision rules: /vegan-baseline/protocol-engine.json
- Evidence scoring: /vegan-baseline/evidence-scoring.json
- LLM context: /vegan-baseline/llms.txt
- Open datasets: CSV & JSON exports (CC BY 4.0)
Frequently asked questions
Which supplements should vegans take?
Based on 106 scientific sources, this protocol identifies 6 nutrients that require supplementation on a vegan diet: Vitamin B12, Vitamin D3, Omega-3 DHA/EPA (from algae), Iodine, Selenium, and Creatine. Each passes strict inclusion criteria requiring convergent evidence from multiple independent research streams.
How much vitamin B12 do vegans need?
1000 µg of cyanocobalamin (sublingual), taken twice per week (e.g. Monday and Thursday). This form has the strongest evidence base. Methylcobalamin is not recommended as the primary form due to lower stability.
What is the best vegan omega-3 supplement?
Algae oil providing 300–500 mg of DHA + EPA combined, daily. Plant-based ALA (from flaxseed, chia) converts to DHA at only 2–5%, which is insufficient. Algae oil is the only vegan source of preformed DHA and EPA.
Do vegans need creatine?
Yes. Creatine is found exclusively in animal tissue. Vegans have significantly lower muscle creatine stores compared to omnivores. 3 g/day of creatine monohydrate is the evidence-based recommendation for maintaining optimal levels.
Is this medical advice?
No. NutraProtocol provides a non-medical nutritional baseline for healthy adults (18+). It is not a substitute for professional medical advice. If you are pregnant, breastfeeding, taking medication, or have health conditions, consult a healthcare provider.
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